Non-dietary personal pesticide exposure https://www.sciencedirect.com/science/article/pii/S0160412025004854 How hard it is to avoid pesticide exposure https://www.theguardian.com/environment/2025/oct/24/i-was-contaminated-study-reveals-how-hard-it-is-to-avoid-pesticide-exposure Even people who live far from farms are exposed to several different types of pesticides from non-dietary sources – including banned substances

Higher cfPWV may exacerbate, whereas lower cfPWV may buffer, the effects of neurodegeneration—helping to preserve cognitive function in older adults https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70554 Stiff arteries may amplify early memory decline in older adults https://medicalxpress.com/news/2025-10-stiff-arteries-amplify-early-memory.html

Immediate skin-to-skin contact between newborns and their mothers offers a better start in life, improving a number of key health metrics https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003519.pub5/full Benefits, including exclusive breastfeeding, optimal body temperatures and blood sugar levels https://medicalxpress.com/news/2025-10-strong-evidence-skin-contact-birth.html

Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01205-7 Serotonin produced by gut bacteria provides hope for a novel IBS treatment https://medicalxpress.com/news/2025-10-serotonin-gut-bacteria-ibs-treatment.html

Each time you flush the toilet, a plume of tiny droplets of water and faeces are thrown up to 1.5m into the air. Carried with this aerosol-like spray can be bacteria viruses such as those that cause flu, Covid-19 and the winter vomiting bug norovirus https://www.bbc.com/future/article/20251017-why-you-might-want-to-clean-your-toothbrush-more "If you happen to keep your toothbrush close by, then the contents of your toilet bowl could well end up settling on to the bristles you later put into your mouth. There is more risk of directly inhaling infectious microorganisms at the time of flushing, but you might want to think twice about leaving the toilet seat up before you flush in future"

Deep sleep supports memory via brain fluid and neural rhythms https://medicalxpress.com/news/2025-10-deep-memory-brain-fluid-neural.html A myriad of research has shown that crucial cognitive processing manifests in slow-wave and rapid-eye movement (REM) sleep

Sleep practices during infant illnesses may increase risk of sudden infant death https://medicalxpress.com/news/2025-10-infant-illnesses-sudden-death.html Many caregivers in the study reported shifts away from recommended safe sleep practices, such as placing infants on their backs to sleep, during infant illness. The most common changes included increased bed-sharing, sleeping on non-recommended sleep surfaces, and prone or side positioning

BRYAN JOHNSON Want to sleep better and live longer? Try the famous the biohacker's top health hack! https://www.youtube.com/watch?v=XXPISZI_big Smoking is the worst thing anybody can do for their body! Not exercising is the second worst thing you can do. Avoid doom scrolling at all costs!

"Shortness of breath" is listed by the NHS as a sign of Covid and not flu. This is more commonly found in the case of illnesses such as Covid or respiratory syncytial virus (RSV) - This is the one key symptom that means you have Coronavirus, and not flu https://www.independent.co.uk/news/health/do-i-have-covid-or-flu-symptoms-vaccine-b2846347.html

Urolithin A: is not known to be found in any food but rather forms as the result of transformation of ellagic acids and ellagitannins by the gut microflora https://en.wikipedia.org/wiki/Urolithin_A Its precursors – ellagic acids and ellagitannins – are e.g. in pomegranates https://www.derstandard.at/story/3000000292411/wikipedia-wird-immer-mehr-von-ki-besucht-immer-weniger-von-menschen The 10 Foods Richest in Urolithin A: There's an important basic principle to understand here: No food directly contains urolithin A. Urolithin A is a metabolite. This means it is first produced in our bodies. Certain gut bacteria produce it by converting precursors called ellagitannins and ellagic acid from our food. The key question, then, is: Which foods contain the most of these precursors? Another important point is that not everyone has the right gut bacteria to efficiently carry out this conversion. It is estimated that only about 40% of people can produce significant amounts of urolithin A from food. Here are the top 10 supermarket foods rich in the precursors (ellagitannins) for urolithin A: Pomegranate: By far the best-known and most potent source, especially the peels and membranes (found in the juice). Walnuts: After pomegranates, one of the best sources. Raspberries: All berries are good, but raspberries (especially the small seeds) are the best. Strawberries Blackberries Pecans Almonds Dried oak mushrooms (shiitake): A lesser-known but good source. Black tea & green tea. Wine or spirits aged in oak barrels: The ellagitannins come from the wood of the barrel. Capsule (500 mg) vs. Pomegranate Juice (0.25 l) – Here we compare two completely different approaches with clear advantages and disadvantages. Daily Urolithin A Capsule (500 mg) – Advantages: Guaranteed Dose: You receive a precise, high-dose amount of the pure end product. The effect is not dependent on your gut bacteria. Everyone can benefit. Targeted Effect: Research on urolithin A focuses on one main benefit: the stimulation of mitophagy. This is the body's natural process for eliminating and recycling damaged mitochondria (the "powerhouses" of our cells). Health Effects: Improved mitophagy is associated with better muscle function, increased endurance, and a slowing of cellular aging processes. No Sugar: You get the active ingredient without unwanted calories or sugar. Daily Pomegranate Juice (0.25 l) – Benefits: Broad Spectrum: You'll not only be consuming the precursors for urolithin A, but also vitamins (vitamin C, K), minerals, and a variety of other powerful antioxidants (e.g., punicalagins). Disadvantages: Uncertain Conversion: As mentioned above, there's no guarantee your body will even produce urolithin A from it. You could drink the juice and produce only minimal amounts of the desired substance. High sugar content: 0.25 liters of supermarket pomegranate juice contains about 30-35 grams of sugar. This is a significant amount, which, if consumed daily, can impact blood sugar levels and cause other health problems. Comparison conclusion: If your goal is targeted and guaranteed intake of urolithin A to promote mitophagy, the capsule is the far superior and more reliable method. Juice is a healthy beverage, but unreliable as a source of urolithin A and is very high in sugar. Part 4: Does Bryan Johnson take urolithin A? (Bryan Johnson is the world-renowned biohacker from the "Blueprint" project.) Bryan Johnson takes urolithin A daily. According to his current, publicly available "Blueprint" protocol, he takes: 1,000 mg of urolithin A per day. He has increased the dosage from the original 500 mg to 1,000 mg. This is part of its comprehensive approach to promoting cellular health and longevity.

Forget youthful brilliance — the human mind actually peaks at 60 https://www.dailymail.co.uk/sciencetech/article-15197463/Scientists-reveal-age-brain-reaches-peak.html A new measure of mental and personality traits suggests the late 50s are your cognitive prime https://www.sciencealert.com/study-reveals-the-surprising-age-at-which-your-brain-reaches-its-peak Study Reveals Turning Point When Your Body's Aging Accelerates

Japan declares a flu epidemic — what this means for EU? https://www.nature.com/articles/d41586-025-03367-z Influenza epidemic, with thousands of people infected with the respiratory virus. The number of infections is unusual for this time of year https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/new-pandemic-coming-japan-declares-nationwide-flu-outbreak-over-4000-hospitalised/articleshow/124484790.cms Flu outbreak – over 4000 hospitalised

Intermittent fasting in type 2 diabetes can improve insulin sensitivity, reduce weight, and partially lower HbA1c https://idw-online.de/de/news859628 Studien zeigen, daß Intervallfasten bei Typ-2-Diabetes die Insulinsensitivität verbessern, das Gewicht reduzieren und den HbA1c senken kann

Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy https://www.nature.com/articles/s41590-025-02286-5 AIDS RESEARCH: German researchers discover antibodies against almost all known HIV viruses https://www.mdr.de/wissen/medizin-gesundheit/aids-forschung-hiv-neuer-antikoerper-wirkt-uni-koeln-100.html Die Studie wurde bislang nur im Tiermodell durchgeführt. Dennoch sind die Ergebnisse vielversprechend, da dieser Antikörper theoretisch sowohl zur Prävention, also zur Verhinderung einer HIV-Infektion, als auch zur Therapie, also zur erfolgreichen Kontrolle einer HIV-Infektion, geeignet ist.

Chocolate Intake and Risk of Clinically Apparent Atrial Fibrillation: the Danish Diet, Cancer, and Health Study (2018 Apr 23) https://pmc.ncbi.nlm.nih.gov/articles/PMC5912690/ Accumulating evidence indicates that moderate chocolate intake may be inversely associated with AF risk https://www.deutschesgesundheitsportal.de/2018/03/25/schokolade-koennte-risiko-fuer-vorhofflimmern-reduzieren/

Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid https://www.nature.com/articles/s41392-025-02295-8 Olive oil and avocados, could enhance γδ-T cell immunosurveillance, leading to more effective cancer treatments https://medicalxpress.com/news/2025-10-dietary-fatty-acids-supercharge-cancer.html

Quantitative assessment of the radon (222Rn) decay product 210Pb in human toenails as a sensitive measure of personalized long-term radon gas exposure history https://www.sciencedirect.com/science/article/pii/S016041202500532X Radon is the second leading cause of lung cancer after tobacco smoking https://medicalxpress.com/news/2025-10-scientists-toenail-reveal-radon-exposure.html Toenails hold long-term information about our exposure to radioactive toxicants in our environment, such as radon gas. They are one of our body's archives of past exposure. Measuring radioactive lead in toenails is a promising way to estimate a person's long-term radon exposure

Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport https://www.nature.com/articles/s41392-025-02426-1 Scientists reverse Alzheimer's in mice using nanoparticles https://medicalxpress.com/news/2025-10-scientists-reverse-alzheimer-mice-nanoparticles.html 1 h after injection, we observed a reduction of 50–60% in Aβ

Caffeine can induce cardiac arrhythmias in sensitive persons, but in the general population, moderate caffeine consumption is not associated with an increased risk of atrial fibrillation (AFib) https://www.nejm.org/doi/full/10.1056/NEJMra1816604 Some studies suggest that coffee may reduce the risk of AFib

Born in 1907 in San Francisco, María’s life spanned an impressive 117 years https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791%2825%2900441-0 Maria Branyas Morera, US-born supercentenarian who died in Spain last August, found to have microbiota of an infant https://www.theguardian.com/world/2025/mar/13/supercentenarian-aging-genes-study Supercentenarian https://www.n-tv.de/wissen/Gene-Glueck-und-Joghurt-Geheimnis-von-Supercentenarian-Maria-Branyas-Morera-gelueftet-article25646743.html

Prevalence and Clinical Impact of Postural Orthostatic Tachycardia Syndrome in Highly Symptomatic Long COVID https://www.ahajournals.org/doi/10.1161/CIRCEP.124.013629 Unusual heart rhythm disorder (POTS) is surprisingly common in patients with long COVID https://medicalxpress.com/news/2025-10-unusual-heart-rhythm-disorder-common.html

Most aspirin use in middle-aged adults may be unnecessary under new assessment https://medicalxpress.com/news/2025-10-aspirin-middle-aged-adults-unnecessary.html Applying newer cardiovascular risk equations could sharply reduce the number of middle-aged adults considered candidates for aspirin to prevent heart disease‼️

Air pollution particles discovered hitching a ride around the body on red blood cells https://publications.ersnet.org/content/erjor/early/2025/09/04/2312054100767-2025 Researchers have found the first direct evidence that tiny particles of air pollution stick to red blood cells, meaning they can travel freely around the body https://medicalxpress.com/news/2025-10-air-pollution-particles-hitching-body.html

Covid cases rising with new variants Nimbus and Stratus https://www.bbc.com/news/articles/c3rv3y9jnryo Have you got a razor blade sore throat?

Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2707428 Get your VO2 max as high as possible! You might have heard VO2 max mentioned as a metric that should be on your radar https://www.womenshealthmag.com/uk/health/a68113695/doctor-easy-longevity-tips/ A high VO2 max correlates to better physical fitness and is associated with a lower risk for cardiovascular disease and increased longevity. If you know your VO2 max, you can use it as a tool to help you exercise more efficiently. https://www.health.harvard.edu/staying-healthy/vo2-max-what-is-it-and-how-can-you-improve-it

Maria Branyas wurde 117 Jahre alt und blieb dabei weitgehend frei von Alterskrankheiten. Was kann ihre DNA über Longevity verraten? https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00441-0 Ein internationales Forschungsteam hat erstmals ein vollständiges molekulares Profil der Frau mit der bislang längsten verifizierten Lebensspanne (1907 bis 2024) erstellt. Trotz klassischer Zeichen des Alterns war ihre Zellbiologie erstaunlich „jung”. Bis zu ihrem Tod blieb sie von Krebs oder Demenz verschont. Die Studie liefert neue Hinweise darauf, wie genetische Anlagen und eine günstige Darmflora das Altern verlangsamen können. https://www.fitbook.de/gesundheit/dna-longevity Sie hatte ein exzellentes Mikrobiom: Im Darmmikrobiom dominierte Bifidobacterium, eine „verjüngende” Bakteriengruppe. Ihre Mikrobiom-Vielfalt war deutlich höher als bei gleichaltrigen Kontrollpersonen. Die Forscher vermuteten, dass es eine Korrelation zum Joghurtkonsum der 117-Jährigen geben könnte. Sie aß täglich drei Joghurts, die die Bakterien Streptococcus thermophilus und Lactobacillus delbrueckii enthielten. Diese werden mit der Bildung von Bifidobacterium in Verbindung gebracht. https://www.welt.de/wissenschaft/article68d4dd271e87ea5182edcf5c/Gesund-alt-werden-Was-Forscher-im-Leben-der-117-jaehrigen-Maria-Branyas-entdeckten.html Außerdem aß die Spanierin täglich trank einen Smoothie aus acht verschiedenen Getreidesorten. In ihrem Erbgut fanden die Forscher außerdem mehrere Genvarianten, die mit einer langen Lebensspanne in Verbindung stehen, unter anderem das sogenannte APOE-Allel. Auch neuroprotektive Gene, die Gehirnzellen vor Schäden bewahren, waren bei ihr homozygot vorhanden, also doppelt angelegt. Besonders auffällig: In ihren Proben fehlten alle bekannten Genvarianten, die mit einem erhöhten Sterblichkeitsrisiko oder verkürzter Lebensdauer verbunden sind. ‘World’s Oldest Living Person’ titleholders https://www.grg-supercentenarians.org/wop/ Liste der ältesten Menschen https://de.wikipedia.org/wiki/Liste_der_%C3%A4ltesten_Menschen#%C3%84lteste_Deutsche

Something as simple as the temperature of our food and drinks can have significant effects on our health https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/cold-and-hot-consumption-and-health-outcomes-among-us-asian-and-white-populations/8C45B97637E237244531C653E42D024E Traditional Chinese and Ayurvedic medicine have always warned against excessive consumption of cold foods❗️ https://medicalxpress.com/news/2025-09-links-food-beverage-temperature-mental.html

Poor sleep health is associated with older brain age: the role of systemic inflammation https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00385-8/fulltext Poor sleep may accelerate brain agin https://medicalxpress.com/news/2025-09-poor-brain-aging.html The associations were more pronounced in males and appear to be partially mediated by systemic inflammation