WHAT IS LYME DISEASE? https://apnews.com/article/ticks-lyme-disease-bite-a28b25bc0d6103b02b48b2fbba65b5a3 Not all ticks are infected with disease-causing germs — about 20% to 30% of the blacklegged tick nymphs. Lyme disease symptoms tend to start between 3 and 30 days after a bite occurs and can include fever, headache, fatigue and rash