Pressure on the shinbone: Old mice live 79.5 days longer and stay fit https://www.telepolis.de/article/Druck-aufs-Schienbein-Alte-Maeuse-leben-79-5-Tage-laenger-und-bleiben-fit-11507515.html Strong bones slow down aging https://www.science.org/content/article/bones-may-release-proteins-slow-aging-and-extend-life-span In mice, bone-based tibial loading mechanosensing delays aging and extends extends both healthspan + lifespan https://www.cell.com/cell-metabolism/fulltext/S1550-4131(26)00433-X