R-Alpha-Liponsäure ⟿ dringt in intra- und extrazelluläre wasserlösliche und fettlösliche Strukturen ein ⟿ kann andere oxidierte Antioxidantien wie Vitamin C und E, Glutathion und Coenzym Q10 regenerieren What is R-alpha-lipoic acid and what are its functions in the human body? Alpha-lipoic acid is a sulfur-containing fatty acid that naturally occurs in the human body and can also be found in small amounts in certain foods, such as beef and organ meats. It has both water-soluble and fat-soluble properties due to the two sulfur atoms that are connected in a ring structure. The body produces alpha-lipoic acid, and it is also readily absorbed from the gastrointestinal tract and distributed throughout the body. Alpha-lipoic acid has two main functions in the body. First, it is a coenzyme of enzyme complexes in the mitochondria of every cell, including the pyruvate dehydrogenase complex and alpha-ketoglutarate dehydrogenase complex, which are essential for cellular energy production. Second, alpha-lipoic acid is a powerful and versatile antioxidant that can pass through the blood-brain barrier and protect the brain. It can penetrate both intra- and extracellular water-soluble and fat-soluble structures and can neutralize various types of free radicals, as well as chelate with heavy metals. Additionally, it can regenerate other oxidized antioxidants, such as vitamins C and E, glutathione, and coenzyme Q10, and increase the intracellular content of these antioxidants and other antioxidant enzymes, such as catalase and glutathione reductase. Therefore, alpha-lipoic acid can substantially increase the body's antioxidant capacity, and supplementation with R(+)-alpha-lipoic acid, the natural and superior form, can provide these benefits without the potential negative effects of the synthetic form, S(-)-alpha-lipoic acid. https://orthoknowledge.eu/forschung/alpha-liponsaure/alpha-liponsaure/