Benefits and adverse events of melatonin use in the elderly (Review) https://pmc.ncbi.nlm.nih.gov/articles/PMC8796282/ Melatonin kann neben seiner bekannten Wirkung gegen Schlaflosigkeit das Immunsystem stärken und der Hautalterung vorbeugen. Seine Rolle als Antioxidans und Radikalfänger kann bei topischer Anwendung vor UV-Bestrahlung hilfreich sein, um UV-bedingten Hautschäden und Hautalterung vorzubeugen. Melatonin greift in die Blutdruckregulierung ein und bekämpft insbesondere die Nebenwirkung von Betablockern, nämlich Schlaflosigkeit. Durch die Modulation der Sekretion entzündlicher Zytokine wirkt Melatonin antiviral https://x.com/i/grok/share/6ZZQBpJ3LL28uFnJPLGV99yMY Können 1,5 mg Melatonin pro Nacht, eingenommen eine halbe Stunde vor dem Schlafengehen, Puls und Blutdruck während des Schlafes und in den ersten Stunden nach dem Aufwachen signifikant senken? Wenn ja, kann die Kombination mit 500 mg GABA den Puls und den Blutdruck während des Schlafes und in den ersten Stunden nach dem Aufstehen signifikant senken?

Ω3-Fettsäuren, Vit D + Bewegung scheinen einen dreifachen Schutz vorm Altern zu bieten. „Es ist wissenschaftlich gut belegt, daß Vitamin D unkontrolliertes Zellwachstum verhindert und entzündungshemmend wirkt“ https://www.goodhousekeeping.com/health/diet-nutrition/a64303162/study-omega3-fatty-acids-biolgical-age/ Taking Vit D + Ω3 Every Day Slows Down Aging

Ibuprofen inhibits human sweet taste and glucose detection https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70004 Forscher entdecken neue Wirkung von Ibuprofen https://www.t-online.de/gesundheit/aktuelles/id_100657104/ibuprofen-forscher-entdecken-neue-wirkung-mittel-gegen-diabetes-.html Ibuprofen use is associated with increased risk of out-of-hospital cardiac arrest https://academic.oup.com/ehjcvp/article/3/2/100/2739709

High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple SclerosisThe D-Lay MS Randomized Clinical Trial https://jamanetwork.com/journals/jama/article-abstract/2831270 Clinical trial: High‑dose vitamin D significantly reduces disease activity in early multiple sclerosis onset https://medicalxpress.com/news/2025-03-highdose-vitamin-d-significantly-disease.html Conclusions: Oral cholecalciferol 100 000 IU every 2 weeks significantly reduced disease activity in CIS and early relapsing-remitting MS. These results warrant further investigation, including the potential role of pulse high-dose vitamin D as add-on therapy

BRD – abartige Abzocke ³❗️ Von Rumänien abgehängt: in Deutschland zahlt man 100-mal mehr für schnelles Internet❗️ In der EU gibt es kein Land, in dem schnelles stationäres Breitbandinternet so absurd teuer ist wie in🇩🇪 https://t3n.de/news/deutschland-internet-preis-100-fach-1678998/ 1 Cent pro Megabit in Rumänien❗️ Ein Abschalttermin für das völlig veraltete, extrem überteuerte DSL ist nicht vor den 2030er-Jahren zu erwarten

Probiotics and Fever Duration in Children With Upper Respiratory Tract Infections https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831509 In this randomized clinical trial, administering a probiotic mixture shortened fever duration by 2 days compared with placebo https://medicalxpress.com/news/2025-03-probiotic-boosters-shorten-fever-duration.html The probiotic group received daily single dose of 0.5 mL probiotic mixture containing Bifidobacterium breve M-16V, Bifidobacterium lactis HN019, and Lactobacillus rhamnosus HN001 for 14 days. The placebo group received daily single dose of 0.5 mL placebo for 14 days

Cafestol and kahweol concentrations in workplace machine coffee compared with conventional brewing methods https://www.nmcd-journal.com/article/S0939-4753(25)00087-0/fulltext Most coffees from workplace brewing machines contain higher cholesterol-elevating substances than paper-filtered coffee ☕️ https://medicalxpress.com/news/2025-03-cholesterol-elevating-substances-coffee-machines.html

Magnesium transport across the blood-brain barriers https://www.ncbi.nlm.nih.gov/books/NBK507259/ The BBB plays a pivotal role in the tight regulation and rigorous stabilization of the chemical composition of brain ECF, thus promoting normal neuronal signaling https://www.verywellhealth.com/magnesium-l-threonate-8732187 Unlike other supplemental forms of magnesium, magnesium L-threonate can cross the blood-brain barrier, offering a slew of cognitive benefits. Although research is limited, studies thus far show a potential benefit of magnesium L-threonate for anxiety and stress, ADHD, sleep, and cognitive function

Women need slightly more sleep than men because of their changing hormones https://www.nytimes.com/2025/02/18/well/sleep-needs-for-women-versus-men.html A study shows that women sleep for 11 min more than men do; it’s representative of real differences between the sexes. Women are far more likely than men to experience insomnia❗️

Lipoprotein (a) Kardiovaskuläre Prävention: Neues zum Lipoprotein (a) https://www.aerzteblatt.de/archiv/kardiovaskulaere-praevention-neues-zum-lipoprotein-a-2710398a-7e8b-4bff-86c1-a5cc5ca3e07f Jede 3. Person weist eine Serumkonzentration oberhalb der als optimal einzustufenden Grenzwerte von < 30 mg/dl beziehungsweise <75 nmol/l auf. Bei jedem Fünften liegt eine Lp(a)-Konzentration von >50 mg/dl beziehungsweise >125 nmol/l vor

COVID-19: Schulen, Kitas, Restaurants, Friseure, Läden geschlossen – Bordells, Laufhäuser auch🤣und wurden vom Staat in Millionenhöhe fürstlich entschädigt❗ Vor 5 Jahren wurde das Alltagsleben in der EU im Kampf gegen die Ausbreitung von Corona ziemlich reduziert https://www.t-online.de/finanzen/boerse/ticker/hintergrund-erster-lockdown-vor-fuenf-jahren-was-bleibt-/0DB4D800E863BF51/ Coronavirus

How lateral flow tests are becoming a diagnostic gamechanger https://www.theguardian.com/science/2025/mar/09/how-lateral-flow-tests-are-becoming-a-diagnostic-gamechanger FTs are designed to rapidly detect a molecule of interest without the need for specialised, costly equipment, by incorporating highly specific antibodies into a plastic cartridge

Can melatonin supplements really 'reverse' DNA damage caused by lack of sleep? https://medicalxpress.com/news/2025-03-melatonin-supplements-reverse-dna-lack.html Melatonin not only has antioxidant properties but may also boost specific genes involved in the repair process

Eicosapentaensäure (EPA) und Docosahexaensäure (DHA), die in hohen Mengen in Fischöl enthalten sind, können laut Studie eine bestehende Insulinresistenz verringern und zudem Blutzucker, Entzündungs- und Blutfettwerte verbessern. Auf diese Weise könnten Omega-3-Fettsäuren auch bei Diabetes hilfreich sein https://www.fitbook.de/gesundheit/omega-3-fettsaeuren-diabetes

LiVE Webcam of the peregrine falcons 🚩 Der Brutplatz der Wanderfalken ist im Sinwellturm der Nürnberger Kaiserburg. Eine Webcam zeigt den Innenraum des Nistkastens, die andere das an den Nistkasten anschließende Abfluggitter mit Blick über die Stadt Nürnberg https://lebensraum-burg.de/Wanderfalke/Webcam LiVE Webcam of the peregrine falcons🚩

Bettwanzen reisen mit um die Welt – in der Dreckwäsche❗️ https://de.euronews.com/2017/09/29/low-cost-tourismus-bettwanzen-reisen-im-koffer-um-die-welt Dirty laundry a powerful magnet for bedbugs, study finds❗️ https://www.theguardian.com/environment/2017/sep/28/dirty-laundry-a-powerful-magnet-for-bedbugs-study-finds The biting parasites have soared during the past decade

Coffee was once believed to be bad for our health, but research suggests that drinking coffee may actually benefit us https://www.bbc.com/reel/video/p0kvt6g6/why-drinking-coffee-can-benefit-your-health Why drinking coffee can benefit your health

KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids https://www.cell.com/neuron/abstract/S0896-6273(25)00114-X New Antibody Therapy Shows Promise Against All COVID Variants – And the Future Ones Too https://scitechdaily.com/new-antibody-therapy-shows-promise-against-all-covid-variants-and-the-future-ones-too/

New Antibody Therapy Shows Promise Against All COVID Variants – And the Future Ones Too https://scitechdaily.com/new-antibody-therapy-shows-promise-against-all-covid-variants-and-the-future-ones-too/ A research team has found a way to counter this challenge by pairing two antibodies — one that anchors to a stable part of the virus and another that blocks infection

How to eat and drink fewer microplastics. Scientists are finding microplastics throughout the human body. Here are some simple strategies to limit your exposure https://www.washingtonpost.com/climate-solutions/2025/03/04/ways-to-avoid-microplastics-food-water/ Drinking bottled water could be introducing you to thousands of microscopic pieces of plastic❗️

Role of potassium in regulating blood flow and blood pressure https://journals.physiology.org/doi/full/10.1152/ajpregu.00491.2005 Potassium softens vascular endothelium and increases nitric oxide release https://www.pnas.org/doi/10.1073/pnas.0813069106 Potassium’s Blood Pressure Effects you’ve Never Heard https://www.youtube.com/watch?v=CoYZe9P3zVw

"I recommend being in the office at least every weekday," said Sergey Brin in a recent internal message seen by the New York Times. He added that "60 hours a week is the sweet spot of productivity" in the message to employees working on GOOGL AI Gemini https://www.nytimes.com/2025/02/27/technology/google-sergey-brin-return-to-office.html

Some plastic will almost certainly end up in your food! Microplastics can’t be avoided completely, but even small steps in the right direction can help significantly https://www.theguardian.com/lifeandstyle/2025/mar/01/how-to-avoid-microplastics Tea bags can release billions of particles, and microwavable plastic is also a problem

‘We’re losing decades of our life to this illness’: long Covid patients on the fear of being forgotten https://www.theguardian.com/society/2025/mar/02/were-losing-decades-of-our-life-to-this-illness-long-covid-patients-on-the-fear-of-being-forgotten Five years on from March 2020, millions of people still face debilitating symptoms, with huge repercussions on public health and productivity

Repairing DNA Damage: Scientists Identify New Benefits of Melatonin Supplementation https://scitechdaily.com/repairing-dna-damage-scientists-identify-new-benefits-of-melatonin-supplementation/ Findings warrant future larger-scale studies that examine varying doses of melatonin supplements and longer-term impacts of melatonin use

PFAS increase likelihood of death by cardiovascular disease. Researchers were able to compare records of people who drank polluted water in Italy, with neighbors who did not https://www.theguardian.com/environment/2024/apr/29/pfas-death-cardiovascular-disease Strong evidence of an association of PFAS exposure and cardiovascular mortality