How to Become a Super Ager https://edition.cnn.com/audio/podcasts/chasing-life/episodes/b3d6cbca-37bb-11ef-8219-4309e65560b9 Can you maintain good health into your 80s and beyond? Cardiologist Dr. Eric Topol says yes. He joins Dr. Sanjay Gupta explain why preventing the onset of major diseases is key to extending your life and health-span

The impact of REM-sleep behavior disorder on people with Parkinson’s disease and their partners https://www.nature.com/articles/s41531-025-00986-1 REM sleep behavior disorder affects both Parkinson’s patients, partners https://parkinsonsnewstoday.com/news/both-parkinsons-patients-partners-affected-rem-sleep-behavior-disorder/ Sleep disorders increase dementia risk https://www.bbc.com/news/articles/ckg4lgrnmnjo

The findings showed that prolonged paracetamol use was associated with an increased risk of peptic ulcers, heart failure, hypertension and chronic kidney disease https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/acr.25471 You should never take Paracetamol in old age❗️ https://www.t-online.de/gesundheit/aktuelles/id_100746438/paracetamol-im-alter-neue-studie-warnt-vor-ernsthaften-nebenwirkungen.html https://www.nottingham.ac.uk/news/paracetamol-safety-for-older-people

Married people were more likely to develop Alzheimer's than their peers who lived alone❗️ The difference was particularly pronounced among people who had never been married. Their risk of developing dementia was 40% lower than that of married people❗️ https://www.t-online.de/gesundheit/aktuelles/id_100743536/demenz-ehe-schuetzt-wohl-doch-nicht-vor-der-erkrankung-studie.html Verheiratete erkrankten häufiger an Alzheimer als ihre alleinlebenden Altersgenossen❗️ Besonders deutlich wurde der Unterschied bei Menschen, die nie verheiratet waren. Ihr Risiko, an Demenz zu erkranken, war um 40 % geringer als bei Verheirateten❗️

Influenza Vaccination for Cardiovascular Prevention: Further Insights from the IAMI Trial and an Updated Meta-analysis https://pmc.ncbi.nlm.nih.gov/articles/PMC9310360/ Grippeimpfung sofort nach dem Herzinfarkt sollte Standard werden https://springermedizin.de/kardiologie/-grippeimpfung-sofort-nach-dem-herzinfarkt-sollte-neuer-standard/24654322 Herzschutz durch Impfung: Erkenntnisse aus der Kardiologie | Dr. Heart https://www.youtube.com/watch?v=cbBLwQTDOjQ

Nato rearmament could increase emissions by 200m tonnes a year❗ Researchers say defence spending boosts across world will worsen climate crisis which in turn will cause more conflict https://www.theguardian.com/environment/2025/may/29/nato-military-spending-could-increase-emissions-study-finds The global military buildup poses an existential threat to climate goals❗

How coffee affects a sleeping brain https://medicalxpress.com/news/2025-05-coffee-affects-brain.html Caffeine attenuated slower oscillations such as theta and alpha waves — generally associated with deep, restorative sleep — and stimulated beta wave activity, which is more common during wakefulness and mental engagement

Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease in a Population-Based Cohort (2024 Mar 21) https://pmc.ncbi.nlm.nih.gov/articles/PMC11175631/ There is a strong inverse relationship between caffeine and the risk of Parkinson's https://www.chip.de/news/Parkinson-Risiko-senken-Dieses-Getraenk-reduziert-es-um-40-Prozent_185698906.html

SARS-CoV-2 variants in EU https://www.ecdc.europa.eu/en/covid-19/variants-concern New Dangerous Covid Variant Spreading in Asia, Now in US: New COVID-19 variant found among international travelers to New York https://www.dailymail.co.uk/health/article-14743073/Doctors-warning-covid-virus-new-variant.html Neue Corona-Variante breitet sich in Europa aus https://www.fr.de/panorama/neue-corona-variante-breitet-sich-in-europa-aus-hohe-faehigkeit-der-immunreaktion-zu-entgehen-93749109.html

A single dishwasher cycle involving plasticware can release nearly a million particles❗️ Microplastics are small enough to breach biological barriers such as the blood-brain barrier. The release of microplastics is primarily driven by the dishwasher's heat https://www.dailymail.co.uk/sciencetech/article-14743425/kitchen-task-fueling-dementia-epidemic-microplastics.html During a typical cycle, plastic items are exposed to chemical, thermal, and abrasive cleaning processes – with high temperatures, along with detergent and rinse cycles

Chlorogenic acid CGA in coffee protects you from heart disease https://www.youtube.com/watch?v=iILnDvAHruI Chlorogenic acid intake guidance: health benefits https://pubmed.ncbi.nlm.nih.gov/36576278/ Chlorogenic Acid: A Systematic Review on the Therapeutic Potentials https://www.mdpi.com/2072-6643/16/7/924 https://www.sciencedirect.com/science/article/pii/S2095754824000073

What does it cost per year to charge a smartphone with a battery of 4000–5000 mAh daily – given the high German electricity price of ~40 cents? 🇩🇪 Charging your phone daily will cost you around €2 to €3 per year – a real bargain! Was kostet es pro Jahr, ein Smartphone mit einem Akku von 4000–5000 mAh täglich zu laden – angesichts des hohen deutschen Strompreises von ~40 Cent/kWh? https://www.chip.de/news/Smartphone-jeden-Tag-an-der-Steckdose-Diese-Stromkosten-entstehen-pro-Jahr_184252644.html Das tägliche Laden Ihres Handys kostet Sie ~ 2 bis 3 € pro Jahr – ein echtes Schnäppchen also!

Vitamin D3 and Marine Omega-3 Fatty Acids Supplementation and Leukocyte Telomere Length: 4-Year Findings from the VITAL Randomized Controlled Trial https://www.sciencedirect.com/science/article/abs/pii/S0002916525002552 4-years of supplementation with 2000 IU/day vitamin D3 reduced telomere attrition by 140 bp, suggesting that vitamin D3 daily supplementation with or without n-3 FAs might have a role in counteracting telomere erosion or cell senescence https://www.dailymail.co.uk/health/article-14736021/breakthrough-harvard-study-common-supplement-reverses-aging.html 2000 international units (IU) in pill form every day, the equivalent of one 3.5oz serving of salmon, reverses aging (Harvard study)

Laut Dr. med. SELZ gibt es leider nur 2 empfehlenswerte-B12-Formen: Adenosylcobalamin aus tierischen Produkten: dient zur Energiegewinnung und ist für den Stoffwechsel in den Mitochondrien erforderlich https://www.youtube.com/shorts/bZOODR-6vlQ Methylcobalamin ist wichtig fürs Nervensystem

A common enzyme takes on a surprising role in preventing cancer https://medicalxpress.com/news/2025-05-common-enzyme-role-cancer.html Targeting the regulatory activity of the mitochondrial proline-metabolizing enzyme ALDH4A1 within the MPC complex could be promising for future metabolic interventions in cancer

How Eating Too Much Protein Can Accelerate Aging https://parade.com/health/common-health-habit-accelerates-aging “Too much protein, particularly from animal sources (think eggs, beef, chicken) can chronically activate a key nutrient-sensing pathway in the body called IGF-1, or insulin-like growth factor 1”

Täglich 4000 IE Vitamin D für Stubenhocker sind optimal❗️ 4000 IU of vitamin D daily is optimal for couch potatoes❗️ Die meisten relativ gesunden Menschen mit Hauttyp 2-3 brauchen 4000 Vitamin D täglich, begleitet von den Cofaktoren Magnesium + Vitamin K2, um einen optimalen 25-OH-VD Spiegel von 60 ng zu halten https://www.augsburger-allgemeine.de/panorama/sind-2000-ie-vitamin-d-am-tag-zu-viel-18-5-25-109045564

Health impacts of exposure to synthetic chemicals in food https://www.nature.com/articles/s41591-025-03697-5 Types and of food contaminants, focusing on food contact chemicals and their presence in ultra-processed foods https://www.dailymail.co.uk/health/article-14718869/cancer-causing-chemicals-hidden-food-packaging.html Even 'eco-friendly' containers are a risk

Exploring the bidirectional relationship between sleep disorders and atrial fibrillation https://tehj.springeropen.com/articles/10.1186/s43044-024-00524-z There is a a strong connection between sleep disorders and atrial fibrillation. Untersuchung der wechselseitigen Beziehung zwischen Schlafstörungen und Vorhofflimmern

The German National Library of Medicine just had its first open meeting on the plan for an open and independent PubMed safety net https://absolutelymaybe.plos.org/2025/05/14/germanys-plan-for-an-open-and-independent-pubmed-safety-net/ The big vision is to move past the reliance on any single country’s investment in this core life sciences infrastructure

Association Between Slow-Wave Sleep Loss and Incident Dementia https://jamanetwork.com/journals/jamaneurology/fullarticle/2810957 Low levels of slow-wave sleep were linked to a higher risk of cardiovascular disease and having the APOE ε4 gene, which is linked to Alzheimer's https://www.sciencealert.com/one-stage-of-sleep-seems-critical-for-reducing-risk-of-dementia

Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitive symptoms https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0315486 Long COVID Brain Fog “Very Well Explained” By Altered Levels Of 2 Key Biomarkers https://www.iflscience.com/long-covid-brain-fog-very-well-explained-by-altered-levels-of-2-key-biomarkers-79218

Findings suggest that Bacillus clausii and Bacillus coagulans may serve as effective complementary therapies to mitigate tissue damage and thrombotic events in COVID-19 infections, with no adverse effects observed https://pmc.ncbi.nlm.nih.gov/articles/PMC11763649/ Probiotics have shown efficacy in preventing and reducing infections caused by common viruses, including rotavirus, norovirus, hepatitis, human papillomavirus (HPV), human immunodeficiency virus (HIV), and herpes simplex virus (HSV)

Transforming Psoriasis Care: Probiotics and Prebiotics as Novel Therapeutic Approaches https://pmc.ncbi.nlm.nih.gov/articles/PMC10342574/ This 12-week open-label, single-center clinical trial evaluated the efficacy of probiotics (Bacillus subtilis, Bacillus coagulans, and Bacillus clausii)

Elevated Plasma Levels of NET Components in Men with Severe COVID-19 Correlates to Increased Amounts of IL-18 https://onlinelibrary.wiley.com/doi/10.1002/eji.202451546 Discovery may explain why more men are affected by severe COVID-19 https://medicalxpress.com/news/2025-05-discovery-men-affected-severe-covid.html

Samsung mit Android 15 + One UI 7: geänderte Schnelleinstellungen sofort rückgängig machen❗️ https://www.giga.de/tech/samsung-handy-mit-android-15-und-one-ui-7-diese-aenderung-habe-ich-sofort-rueckgaengig-gemacht--01JTR45SZJKPZM0ZCT9HAY10DV One significant change in Samsung’s One UI 7 is the separation of Quick Settings and the notification panel. Here’s how to change it back❗️ https://9to5google.com/2025/05/05/samsung-changed-quick-settings-in-one-ui-7/

The silent epidemic Peripheral neuropathy, a condition that occurs when nerves in the extremities become damaged https://www.journee-mondiale.com/en/the-nutritional-prescription-can-these-targeted-compounds-mend-damaged-nerves/ Vitamin B12: Es hilft, die geistige Leistungsfähigkeit zu erhalten, und schützt vor kognitivem Abbau im Alter https://www.t-online.de/gesundheit/aktuelles/id_100712314/schlaganfallrisiko-und-vitamin-b12-mangel-studien-zeigen-zusammenhang.html

Heart’s Rhythm May Help Forecast Cognitive Longevity https://neurosciencenews.com/heart-rhythm-cognition-28850/ Healthy hearts exhibit complex, adaptive rhythms that reflect resilience to change.Researchers used wearable pulse oximeters and found that higher complexity predicted slower cognitive decline in seniors

"Obicetrapib offers a promising new option — not only did it lower LDL cholesterol by over 30%, but we also saw a reduction in lipoprotein(a)"❗ Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk. Obicetrapib is a highly selective cholesteryl ester transfer protein inhibitor that reduces low-density lipoprotein (LDL) cholesterol levels https://www.nejm.org/doi/10.1056/NEJMoa2415820 A clinical trial tested a once-daily oral medication called Obicetrapib, and found it significantly lowered both LDL cholesterol and lipoprotein(a), [Lp(a)], two key contributors to cardiovascular disease https://medicalxpress.com/news/2025-05-cholesterol-pill-high-heart.html

Scientists use AI facial analysis to predict cancer survival outcomes https://www.thelancet.com/journals/landig/article/PIIS2589-7500(25)00042-1/fulltext FaceAge algorithm outperforms some clinicians’ life expectancy forecasts. A photo like a simple selfie contains important information that could help to inform clinical decision-making

🎶 played at the Airport https://youtube.com/watch?v=1MIb7RkePSk Peter Buka is a pianist born in Hungary in 1997 and is now one of the most popular piano superstars on YouTube. He started playing the piano at the age of 7 https://www.youtube.com/watch?v=XA4zn5WL5DM

Dose-response relationship between evening exercise and sleep https://www.nature.com/articles/s41467-025-58271-x Later exercise timing + higher exercise strain are associated with shorter sleep duration, higher nocturnal resting heart rate, and lower nocturnal heart rate variability https://www.youtube.com/watch?v=lKM9OB6qHCE

In addition to blood pressure reduction, magnesium regulates intracellular calcium, sodium, potassium. Oral magnesium acts as a natural calcium channel blocker. The combination of increased intake of magnesium and potassium coupled with reduced sodium intake is more effective in reducing BP than single mineral intake and is often as effective as one antihypertensive drug in treating hypertension. Reducing intracellular sodium and calcium while increasing intracellular magnesium and potassium improves BP response. Magnesium also increases the effectiveness of all antihypertensive drug classes. Magnesium intake is correlated with reductions in CVA, CVD, arrhythmias, insulin resistance, diabetes mellitus. One of the mechanisms by which magnesium lowers BP is by acting like a natural calcium channel blocker. Magnesium competes with sodium for binding sites on vascular smooth muscle cells, increases prostaglandin E, binds to potassium in a cooperative manner, induces endothelial‐dependent vasodilation, improves endothelial dysfunction in hypertensive and diabetic patients, decreases intracellular calcium and sodium, and reduces blood pressure https://pmc.ncbi.nlm.nih.gov/articles/PMC8108907/ Studien belegen, daß Magnesium den Blutdruck signifikant senken kann https://www.augsburger-allgemeine.de/panorama/so-wirkt-sich-magnesium-auf-den-blutdruck-aus-7-5-25-102828530 Studie zeigt einen positiven Effekt bei Tagesdosen von 368 mg für 3 Monate. Die Magnesium-Therapie wirkte sich sowohl auf den systolischen als auch den diastolischen Blutdruck positiv aus.

Genome-wide association meta-analysis of age at onset of walking in over 70000 infants https://www.nature.com/articles/s41562-025-02145-1 Genes influence infants' walking age https://www.bbc.com/news/articles/clywyrr5prwo The onset of walking is used as a robust clinical marker for brain and behavioural development

Protection of Alzheimer’s disease progression by a human-origin probiotics cocktail https://www.nature.com/articles/s41598-024-84780-8 The gut-brain connection: Harmful viruses in the gut may contribute to dementia https://medicalxpress.com/news/2025-05-probiotic-cocktail-ward-dementia.html Developing a probiotic cocktail that may help ward off dementia

Influence of Ibuprofen on glycerophospholipids and sphingolipids in context of Alzheimer´s Disease https://www.sciencedirect.com/science/article/pii/S0753332225001635 Adverse effects: Ibuprofen increased the amount of triacylglycerides which can be deposited in cells as fat droplets https://www.zwp-online.info/zwpnews/dental-news/branchenmeldungen/wie-ibuprofen-den-fettstoffwechsel-im-gehirn-beeinflusst

5 Vitamin and Supplement Combinations You Should Avoid https://www.goodhousekeeping.com/health/diet-nutrition/a64620677/vitamins-you-shouldnt-mix/ Nehmen Sie zuerst Vitamin B12 ein und warten Sie mindestens 2 h auf Vitamin C. Sie können Vitamin B12 mit einem leichten Frühstück kombinieren – die Einnahme auf nüchternen Magen ist ebenfalls möglich

What exactly is brain fog? Here’s what scientists are finding out https://www.nationalgeographic.de/2025/04/das-vernebelte-gehirn Research is starting to reveal multiple potential causes from inflammation to a leaky blood-brain barrier https://www.nationalgeographic.com/health/article/what-is-brain-fog-causes Brain Fog – Gehirnnebel oder kognitive Störung?

Wikipedia ist heute oldschool, und der Lehrer fragt sich, ob ChatGPT & Co. im Einsatz war ... https://www.derstandard.at/story/3000000268126/wikipedia-baut-jetzt-ein-bisschen-auf-ki Supporting Wikipedia’s moderators and patrollers with AI-assisted workflows that automate tedious tasks in support of knowledge integrity https://wikimediafoundation.org/news/2025/04/30/our-new-ai-strategy-puts-wikipedias-humans-first/