In addition to blood pressure reduction, magnesium regulates intracellular calcium, sodium, potassium. Oral magnesium acts as a natural calcium channel blocker. The combination of increased intake of magnesium and potassium coupled with reduced sodium intake is more effective in reducing BP than single mineral intake and is often as effective as one antihypertensive drug in treating hypertension. Reducing intracellular sodium and calcium while increasing intracellular magnesium and potassium improves BP response. Magnesium also increases the effectiveness of all antihypertensive drug classes. Magnesium intake is correlated with reductions in CVA, CVD, arrhythmias, insulin resistance, diabetes mellitus. One of the mechanisms by which magnesium lowers BP is by acting like a natural calcium channel blocker. Magnesium competes with sodium for binding sites on vascular smooth muscle cells, increases prostaglandin E, binds to potassium in a cooperative manner, induces endothelial‐dependent vasodilation, improves endothelial dysfunction in hypertensive and diabetic patients, decreases intracellular calcium and sodium, and reduces blood pressure https://pmc.ncbi.nlm.nih.gov/articles/PMC8108907/ Studien belegen, daß Magnesium den Blutdruck signifikant senken kann https://www.augsburger-allgemeine.de/panorama/so-wirkt-sich-magnesium-auf-den-blutdruck-aus-7-5-25-102828530 Studie zeigt einen positiven Effekt bei Tagesdosen von 368 mg für 3 Monate. Die Magnesium-Therapie wirkte sich sowohl auf den systolischen als auch den diastolischen Blutdruck positiv aus.