Study finds melatonin may ease chronic pain Melatonin shows promise as low-cost pain relief option for musculoskeletal pain (published on July 1, 2026) https://www.sydney.edu.au/news-opinion/news/2026/07/01/study-finds-melatonin-may-ease-chronic-pain.html For postoperative pain, melatonin is more effective than placebo https://journals.lww.com/pain/fulltext/10.1097/j.pain.0000000000004045~efficacy-and-effectiveness-of-melatonin-for-the-management