High levels of EPA in fish oil supplements may hinder brain recovery after repetitive mild traumatic brain injury (TBI). Researchers found that EPA can disrupt the brain’s vascular repair mechanisms, potentially increasing the risk of long-term neurodegenerative conditions https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00213-5 Researchers concluded that while fish oil supplements have been shown to protect the brain against cognitive decline, this may not be true for those who have been diagnosed with brain injuries. While DHA is known to support neuron structure and brain health, long-term intake of EPA behaves differently, with limited integration into cell membranes and potential to cause harmful metabolic shifts in the brain after repetitive mild traumatic brain injury https://scitechdaily.com/scientists-uncover-potential-brain-risks-of-popular-fish-oil-supplements/