Aspartame decreases fat deposits in mice at a cost of mild cardiac hypertrophy and reduced cognitive performance https://www.sciencedirect.com/science/article/pii/S0753332225010856 Aspartame sweetener cuts fat, but may harm heart and brain—even at low doses https://medicalxpress.com/news/2025-12-aspartame-sweetener-fat-heart-brain.html