Sleep loss induces cholesterol-associated myelin dysfunction https://www.pnas.org/doi/10.1073/pnas.2523438123 How sleep loss damages our brain's wiring https://medicalxpress.com/news/2026-02-loss-brain-wiring.html Cholesterol deficiency severely disrupts the creation, maintenance, and repair of the myelin sheath. Because myelin consists of a high amount of cholesterol, its deficiency or improper recycling by these cells stops repair and regeneration, causing neurological issues