Inulin, a prebiotic fibre, modulates the gut microbiome: Effect of Inulin on Pain Sensitivity in People with Osteoarthritis https://www.mdpi.com/2072-6643/18/5/714 Inulin has an effect on pain perception as it acts as a prebiotic, meaning it feeds beneficial gut bacteria https://www.dailymail.co.uk/health/article-15642775/Gut-health-supplements-relieve-crippling-osteoarthritis-pain-affects-millions-new-study-finds.html